This preclinical study evaluated whether thrombin-preconditioned mesenchymal stem cells from Wharton’s jelly — a tissue in the umbilical cord — could help treat neonatal hypoxic-ischemic brain injury. Preconditioning the cells may boost their healing effects.

The findings support the development of new regenerative therapies for newborns who experience oxygen deprivation at birth, a serious cause of long-term disability.

This is a research reference from our clinical library. Approved by the Chambers Clinic Team — last reviewed May 28, 2026.